张宇昕

博士，讲师

汉族，从事中药活性成分发现及作用机制研究，在国内外学术期刊发表论文20余篇。

学习经历：

代表性成果：

(1) Zhang Yuxin^#; Wang Xing^#; Li Xi; Peng Sha; Wang Shifeng; Huang Christopher Z; Huang Corine Z; Zhang Qiao; Li Dai; Jiang Jun; Ouyang Qin; Zhang Yanling; Li Shiyou^*; QiaoYanjiang^*; Identification of a specific agonist of human TAS2R14 from Radix Bupleuri through virtual screening, functional evaluation and binding studies, Scientific Reports, 2017, 7(1): 12174.

(2) Zhang Yuxin^#; Wang Xing^#; Wang Shifeng; Zhang Yanling^*; QiaoYanjiang^*; Traditional Chinese Bitter Flavor theory: Is there any relation with taste type II receptors?,European Journal of Integrative Medicine, 2016, 8(6): 980-990.

(3) Zhang Yuxin^#; Wang Xing^#; Wang Shifeng; Zhang Qiao; Peng Sha; Li Xi; Zhang Yanling^*; QiaoYanjiang^*; In silico investigation of the association of the TRPM8 ion channel with the pungent flavor of Chinese herbs, Journal of Traditional Chinese Medical Sciences, 2016, 3(4): 248-255.

(4) Wang Xing^#*; Zhang Yuxin^#; Yang Ying; Wu Xia; Fan Hantian; QiaoYanjiang^*; Identification of berberine as a direct thrombin inhibitor from traditional Chinese medicine through structural, functional and binding studies, Scientific Reports, 2017, 7(1): 44040.

(5) Zhang Yuxin; Ning Zhangchi; Lu Cheng^*; Zhao Siyu; Wang Jianfen; Liu Baoqin; Xu Xuegong; Liu Yuanyan^*; Triterpenoid resinous metabolites from the genus Boswellia: pharmacological activities and potential species-identifying properties, Chemistry Central Journal, 2013, 7(1): 153.

(6) 张宇昕;王星; 刘青; 翟晨曦; 栗世铀; 乔延江, 内源表达T2R38受体活化方法的构建及其在中药苦味药性研究应用中的探讨, 中华中医药杂志, 2016, (10): 3981-3984.

(7) Zhi Xin Wang; Yu Xin Zhang; Yan Ling Zeng; Xi Li; Zhao Chen; Jia Ming Luo; Yang Zhang; Yan Ling Zhang; Yan Jiang Qiao, Discovery of TAS2R14 Agonists from Platycodon grandiflorum Using Virtual Screening and Affinity Screening Based on a Novel TAS2R14-Functionalized HEMT Sensor Combined with UPLC–MS Analysis, Journal of Agricultural and Food Chemistry, 2018, 66(44): 11663-11671.

(8) Wang Shifeng; Zhang Yuxin; Zhang Qiao; Peng Sha; Shen Chen; Yu Yangyang; Zhang Minyu; Yang Wei; Wu Qinghua; Zhang Yanling; Li Shiyou; QiaoYanjiang, Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri, Environmental Toxicology and Pharmacology, 2017, 52: 129-137.

(9) Wang Xing; Zhang Yuxin; Liu Qing; Ai Zhixin; Zhang Yanling; Xiang Yuhong; QiaoYanjiang, Discovery of Dual ETA/ETB Receptor Antagonists from Traditional Chinese Herbs through in Silico and in Vitro Screening, International Journal of Molecular Sciences, 2016, 17(3): 389.